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The treatment
AVLX-144
Clinical trials progressing
We are a biotechnology company developing innovative treatments for acute conditions such as acute ischemic stroke (AIS) and subarachnoid haemorrhage (SAH). In October 2020 we administered a first dose of our lead compound AVLX-144 to a human volunteer in a Phase 1 clinical study.
Acute ischemic stroke is a leading cause of death and disability worldwide with few treatment options available, while subarachnoid haemorrhage is a particular form of stroke and an orphan indication. Based on positive results from our extensive preclinical characterization of AVLX-144 and our first clinical trials results we are convinced that we have a unique opportunity to make a transformative difference for patients,
Current Status
AVLX-144
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Stroke costs the United States an estimated $34 billion each year (which includes cost of healthcare, medicine, rehabilitation, and missed workdays)
18k
Stroke costs the United States an estimated $34 billion each year (which includes cost of healthcare, medicine, rehabilitation, and missed workdays)
124m
Stroke costs the United States an estimated $34 billion each year (which includes cost of healthcare, medicine, rehabilitation, and missed workdays)
18k
Stroke costs the United States an estimated $34 billion each year (which includes cost of healthcare, medicine, rehabilitation, and missed workdays)
Latest News
AVLX-144
May 26, 2021
Successfully completes phase 1 clinical trial
A compound developed by Danish researchers from the University of Copenhagen could be the key to one of the greatest unsolved challenges in modern medicine.…
October 12, 2020
A game-changing treatment for acute ischemic stroke
Acute ischemic stroke is a leading cause of death and disability worldwide with few treatment options available, while subarachnoid haemorrhage is a particular…
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Frontpage
The treatment
AVLX-144
Avilex Pharma is a clinical stage company developing best in class neuroprotectants
Avilex Pharma is developing AVLX-144, a PSD-95 inhibitor and best-in-class neuroprotectant to treat patients suffering from acute conditions such as subarachnoid hemorrhage and acute ischemic stroke.
Avilex Pharma is also developing a pipeline of neuroprotectants for multiple Indications. Inhibition of PSD-95 has been clinically validated and AVLX-144 provides a unique opportunity for orphan and broad indications
Current Status
Acute ischemic stroke
4
Every 4 minutes, someone dies of stroke - third most common cause of death – leading cause of long-term disability
34b
Stroke costs the United States an estimated $34 billion each year (includes cost of healthcare, medicine & missed work days).
1
Only one drug tissue plasminogen activator (tPA) is approved for ischemic stroke, but less than 10% receive treatment.
34b
Stroke costs the United States an estimated $34 billion each year (includes cost of healthcare, medicine & missed work days).
Latest News
from Avilex Pharma
December 17, 2021
Press Release: Avilex Pharma and Simcere announce strategic partnership
Avilex Pharma and Simcere announce strategic partnership to develop and commercialize novel treatments for acute ischemic stroke in greater china
May 26, 2021
Successfully completes phase 1 clinical trial
A compound developed by Danish researchers from the University of Copenhagen could be the key to one of the greatest unsolved challenges in modern medicine.…
December 17, 2021
Press Release: Avilex Pharma and Simcere announce strategic partnership
Avilex Pharma and Simcere announce strategic partnership to develop and commercialize novel treatments for acute ischemic stroke in greater china